Synergistic Effect of Schistosomiasis on Hepatitis C Virus (HCV) of Human Liver Indicated by Antioxidant Biomarkers among Egyptian Population

Document Type : Original articles

Authors

1 Zoology Department, Faculty of Science, Suez Canal University, Egypt

2 Zoology Department, Faculty of Science, Damietta University, Egypt

3 Medical lab. in Kafr El-Ghab. Damietta. Egypt

Abstract

The present study aimed to investigate changes of some oxidative stress biomarkers in Egyptian patients infected with schistosoma or/and hepatitis C virus (HCV). Regarding to oxidative stress markers, catalase was significantly higher in HCV- patients group and HCV & Schistosoma infected group compared to Schistosoma infected group. Glutathione peroxidase was significantly higher in all patient groups. Superoxide dismutase was significantly higher in HCV group, as well as HCV & Schistosoma infected patients. Non-significant changes were observed with superoxide dismutase in Schistosoma infected group. Nitric oxide was significantly higher in all patient groups. Catalase, glutathione peroxidase , nitric oxide, and superoxide dismutase levels might be used as monitoring markers for oxidative stress in Schistosoma infection or/and HCV carrier cases.

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